Episode 3: Gina Poe - How sleep restructures our memories and emotions Artwork

Sleep Science Podcast

We spend a third of our lives sleeping, and this podcast is all about understanding sleep. We know a lot about what the brain does in sleep, but we are just starting to understand why it does some of these things, and even more excitingly, how we can take full advantage of sleep and also manipulate it for our own ends. In each episode, neuroscientist Penny Lewis interviews a different sleep researcher, talking about a various aspect of sleep science. Topics will include sleep physiology and medicine, circadian rhythm, how sleep impacts on our memories and creativity, Sleep Engineering for enhanced health and cognition, and the most recent technologies to promote sleep.©SleepSciencePodcast 2021. These materials may be downloaded for personal use only. They may not be shared, distributed or reproduced in any form or for any reason without express permission

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Sleep Science Podcast

Episode 3: Gina Poe - How sleep restructures our memories and emotions

September 15, 2020 • Penny Lewis • Season 1 • Episode 3

In this episode we ask Gina Poe, a sleep scientist from UCLA, about her seminal work on both REM and non-REM sleep. We talk about the role of memory replay in REM, how to measure such replay in rats, as well as the ways in which REM impacts upon emotional representations, and may even help us to combat post traumatic stress disorder (PTSD). We also discuss the importance of sleep spindles for updating conceptual knowledge. Finally, we describe Professor Poe's ground-breaking findings on local sleep and how these may change the face of sleep research in the future.

Produced by: Eniko Simo

See Professor Poe's faculty profile:
https://www.ibp.ucla.edu/faculty/gina-poe/

Find the research papers mentioned in this episode here:
https://academic.oup.com/sleep/article/39/12/2201/2706367
https://www.sciencedirect.com/science/article/pii/S096098221831279X?via%3Dihub
https://link.springer.com/article/10.1007/s00221-014-3890-4
https://www.liebertpub.com/doi/10.1089/jwh.2020.8332

Glossary:
EEG = Electroencephalography is an electrophysiological monitoring method for non-invasively recording the electrical activity of the brain via electrodes placed on the scalp.

Heterosynaptic plasticity = when synaptic pathways that were not directly stimulated themselves undergo changes (synaptic plasticity) as a result of neighbouring synapses being stimulated. Often this means that as one pathway is used and strengthened, an unused neighbouring pathway gets weakened.

PTSD = Post-traumatic stress disorder is a mental health condition that's triggered by a terrifying event. Symptoms may include flashbacks, nightmares, and severe anxiety, as well as uncontrollable thoughts about the event.

Schema = a cognitive framework or concept that helps organize and interpret information.

Spindle = distinct brain waves with frequency 11-16 Hz (measured with EEG).

Theta = 4-8 Hz brainwave frequencies.